The results of the most recent MedCline clinical trial, “Treatment of LPR with a Sleep Positioning Device,” were presented at the annual meeting of the American Association of Otolaryngology – Head and Neck Surgery showing MedCline to be an effective treatment for Silent Reflux/LPR.
The results of the most recent MedCline clinical trial, “Treatment of LPR with a Sleep Positioning Device,” were presented at the annual meeting of the American Association of Otolaryngology – Head and Neck Surgery, the world’s largest organization of specialists who treat the ear, nose, throat and related structures of the head and neck. The study results show MedCline™ to be an effective treatment for laryngopharyngeal reflux (LPR), commonly referred to as Silent Reflux.
This study by Cleveland Clinic was the first to evaluate MedCline with this patient population. Silent Reflux/LPR occurs when stomach acid travels up to the throat causing symptoms, such as chronic cough, difficulty swallowing, asthma, sinusitis or a sore throat. Fifty percent of Silent Reflux/LPR patients do not experience heartburn or regurgitation as commonly experienced with Gastroesophageal Reflux Disease (GERD). Silent Reflux/LPR is commonly treated with higher doses of PPI medications for prolonged periods of time.
The study included patients diagnosed with Silent Reflux/LPR. Patients were instructed to sleep on MedCline™ for at least six hours per night for 28 consecutive nights in an at-home setting. Patients were instructed to maintain their current medication regime during the entire study. Symptom data was collected via two validated questionnaires: (1) Nocturnal GERD Symptom Severity and Impact Questionnaire (N-GSSIQ) and (2) Reflux Symptoms Index (RSI) survey. Both questionnaires were completed by patients upon enrollment, after night 14 and after night 28.